Oral dissolving film, also known as oral dissolving film, oral dispersible film, oral fast dissolving film, and oral fast dissolving film, is a new drug delivery system. The 2015 edition of the Chinese Pharmacopoeia defines a film as a film-like preparation made by processing medicines and suitable film-forming materials for oral or mucosal use. The pharmacopoeia includes the compound norethindrone film and clotrimazole film and other film agents.
In 2001, Listerine®, an American oral care brand under the original Pfizer Company, launched Listerine®, which was named the best invention by Time magazine. From 2003 to 2007, the United States and Canada launched more than 50 oral film products, mainly in the OTC and health care products market. The US FDA evaluated the dosage form as "an irreplaceable new dosage form among traditional oral dosage forms."
In 2006, Japan launched the first oral dissolving film prescription drug-Voglibose oral dissolving film. In 2010, the first prescription film ondansetron (Rapidfilm® and Setofilm®) was launched in the United States and Europe. At present, more than 20 oral dissolving film prescription drugs have been marketed internationally, including risperidone, donepezil, sildenafil and so on. With the update of technology and the development of excipients, more and more pharmaceutical companies have begun to pay attention to the development and application of oral membranes.
