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Advantages and disadvantages of ODF

advantage:

Easy to use and carry, no water is needed for delivery, especially suitable for children, elderly patients and bedridden
Patients with dysphagia;

Low energy consumption, less dust, less auxiliary materials, low production cost and high production efficiency;
➢A coating film production line can be applied to large, medium and small batch production, and the packaging line can be as needed
Split metering and packaging is conducive to automated production:

It can replace part of orally disintegrating tablets and freeze-dried tablets;

Can play an efficient and quick-acting role:
The stability of some medicinal films is good.

Disadvantages:

A new production line must be established:
Taste masking is the challenge of film agents;

Not suitable for large doses of drugs.

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If the coating solution is placed for too long, it is easy to layer and precipitate;
The choice of coating backing layer: the coating liquid should have good adhesion, easy to dry after drying
Peel off the film;
The drying air should be from low to high to avoid rapid drying at the beginning, and the surface of the coating liquid
Drying to form a film to prevent the following solution from drying and wrinkling, resulting in uneven surface;
The drying end point should be controlled well: if it is an organic solvent, it must be under the limit, and the residual water
To ensure that the film is soft, too high moisture will cause the film to stick;
When the coating liquid is a mixed solvent or bubbles are introduced, the disintegration time will be shortened.